Citrinin Immunoaffinity Column

Description

volume: 1/3mL  Tests:  1/25/50 T

PriboFast^® Citrinin Immunoaffinity Column

Citrinin

Citrinin is a polyketide mycotoxin and produced by Penicillium citrinum, the Monascus and Aspergillus species. It is a natural toxic metabolite, and has been studied for acute toxicity, nephrotoxicity, genotoxicity, and its carcinogenicity. Citrinin mainly pollutes rice, studies shown that it may be the causative agent of both endemic Balkan kidney disease and swine nephropathy as well a mutagenic agent of the liver. Therefore, there are strict limits and regulations for citrinin toxin in food and grains all over the world.

Product Design

The principle of Citrinin Immunoaffinity Column is an antigen-antibody reaction. Citrinin monoclonal antibodies have been immobilised on the in-column gel. The toxins in the sample are extracted, filtered, diluted and then slowly passed through the immunoaffinity column, where citrinin molecules are specifically bound to the antibodies in gel. The column is then washed to remove unbound other materials. After wash, citrinin toxins can be eluted with elution buffer (methanol-phosphoric acid) and collected into analytical vials for HPLC or LC-MS/MS.

Validated Matrices

This product can selectively extract citrinin toxins in Food, Grains, Corns, Rice, Chili and Monascus Powder Products samples.

Cat. No.	Tests	Volume
IAC-070-3	25/50 T	3 mL